Deep Learning Pipeline for Microscopy Denoising and Registration

A self-adaptive deep learning framework integrating DeepCAD denoising and PyLoReg registration. Designed for high-fidelity restoration of in vivo calcium imaging by eliminating both Poisson noise and complex motion artifacts.

Demo Applications

Continuous 24-hour Single-Cell Resolution Imaging in Freely Behaving Mice enhanced by NeuroPilot

[视频描述 1]

Robust Motion Correction and Single Restoration of Spinal Cord Neurons in Noisy Two-Photon Data

[视频描述 2]

Spatiotemporal Restoration of Low-SNR 3-Photon Volumetric Calcium Imaging

[视频描述 3]

High Fidelity Restoration of Cortex-wide Two-Photon Calcium Imaging in Vivo

[视频描述 4]

Image Restoration for Multiplex Imaging in the Mouse Superficial Barrel Cortex

[视频描述 5]

Motion Correction and Single Extraction of Neuronal Axons in Noisy Spinal Cord Data

[视频描述 6]

High Fidelity Reconstruction of Microcirculation in the Ventral Lumbar Spinal Cord of Freely Moving Mice

[视频描述 7]

Robust Motion Correction and Single Restoration for Comparative Analysis of Neural Population Trajectories in the Mouse LEC and CA1 Retion

[视频描述 8]

Restoration of Mitochondrial Morphology and Topological Fidelity in Noisy Two-Photon Microscopy Data

[视频描述 9]

High-Fidelity Cross Session Tracking of Spinal Neurons Under Varied Simulation Conditions

[视频描述 10]

Robust Spatiotemporal Calcium Signal Extraction from Free-Moving Spinal Cord Imaging Data

[视频描述 11]

Robust Motion Correction and Signal Restoration of Spinal Cord Neurons in Noisy Two-Photon Microscopy Data

[视频描述 12]