Deep Learning Pipeline for Microscopy Denoising and Registration

A self-adaptive deep learning framework integrating DeepCAD denoising and PyLoReg registration. Designed for high-fidelity restoration of in vivo calcium imaging by eliminating both Poisson noise and complex motion artifacts.

Demo Applications

Continuous 24-hour High-Resolution Intravital Imaging in Freely Behaving Mice

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Title

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NeuroPilot-Driven Signal Recovery of Head-mounted Three-photon Calcium Imaging across Cortical and Hippocampal Depths

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Enhanced Large-scale Two-Photon Calcium Imaging of the Mouse Cortex via NeuroPilot

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Image Enhancement for Multiplexed Two-photon vS1 Imaging

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NeuroPilot Performance on Spinal Cord Vascular Imaging

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Robust Motion Correction and Single Restoration in LEC and CA1

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Mitochondrial Calcium Signal Recovery and Morphology Restoration

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Stable Cross-Session Tracking of Spinal Neurons During Varied Stimulation

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Longitudinal Segmentation and Signal Extraction of Spinal Neuronal Activity over 28 Days

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Longitudinal Tracking of Mouse Spinal Cord Neurons over 28 Days

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